Oxandrolone increases free and bound cortisol levels, most likely due to its actions as a cortisol receptor antagonist (7). Additionally, oxandrolone decreases thyroid binding globulin concentrations pretty severely with large increases in thyroxine-binding prealbumin resulting in increased T3 uptake (7). This correlates with the belief that oxandrolone is beneficial in a “cutting stack”. Further evidence comes from studies showing a 4 pound decrease in fat mass with a gain of 7 pounds of lean mass over the course of 12 weeks of treatment with only 20 mg (10 mg, twice daily) of oxandrolone (8). There is also evidence in the literature that oxandrolone enhances ketogenesis (9).
Christ. Finasteride has impotence, loss of interest in sex, trouble having an orgasm, abnormal ejaculation listed as "common" side effects. And "Less serious" side effects also include impotence, loss of interest in sex, or trouble having an orgasm, which may persist after discontinuation. I thought this was rare. Why on earth are these side effects considered non-serious? Does the doctor consider impotence in himself as non-serious? This is really disheartening, that they can list this s**t as non-serious. Fvck off with "non-serious". It's the same with many anti-depressants.
It could be argued that aromatization is a non-issue, as an . could always be employed to counter estrogen conversion. This is true, but I believe there is a simpler way to go about it. In my opinion, the ideal pre-contest MPD cycle should consist of a low dose of testosterone propionate (150-200 mg/week), as at least some estrogen is needed to maintain a healthy looking skin tone. This should be combined with 2-3 other anabolics; preferably 1-2 oral anabolics and 1-2 injectables anabolics. Some good examples of orals include: Anavar, Epistane, and Turinabol. As for injectables, most people usually find the following drugs to be compatible: Primo, Boldenone, and Dihydroboldenone (1-testosterone).