Surgical Anxiety – It is very common for people to experience anxiety before surgery. This is of course a problem for people needing surgical procedures. Having anxiety before an operation can delay or affect the immediate outcome of a surgical procedure. Sedatives can relieve the surgical anxiety of a person but it may have negative side effects. A study by Salah A. Ismail and colleagues April 2009 edition of “Anesthesia & Analgesia”) shows that patients who have been given melatonin experienced less anxiety and pain during an eye surgery.
At normal therapeutic doses, the most common psychological side effects of amphetamine include increased alertness , apprehension, concentration , initiative, self-confidence , and sociability, mood swings ( elated mood followed by mildly depressed mood ), insomnia or wakefulness , and decreased sense of fatigue.   Less common side effects include anxiety , change in libido , grandiosity , irritability , repetitive or obsessive behaviors, and restlessness; [sources 4] these effects depend on the user's personality and current mental state.  Amphetamine psychosis (., delusions and paranoia ) can occur in heavy users.    Although very rare, this psychosis can also occur at therapeutic doses during long-term therapy.    According to the USFDA, "there is no systematic evidence" that stimulants produce aggressive behavior or hostility.