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Triethylene glycol is well established as a relatively mild disinfectant toward a variety of bacteria , influenza A viruses and spores of Penicillium notatum fungi.  However, its exceptionally low toxicity, broad materials compatibility, and low odor combined with its antimicrobial properties indicates that it approaches the ideal for air disinfection purposes in occupied spaces.  Much of the scientific work with triethylene glycol was done in the 1940s and 1950s, however that work has ably demonstrated the antimicrobial activity against airborne, solution suspension, and surface bound microbes. The ability of triethylene glycol to inactivate Streptococcus pneumoniae (original citation: pneumococcus Type I), Streptococcus pyogenes (original citation: Beta hemolytic streptococcus group A) and Influenza A virus in the air was first reported in 1943.  Since the first report the following microorganisms have been reported in the literature to be inactivated in the air: Penicillium notatum spores,  Chlamydophila psittaci (original citation: meningopneumonitis virus strain Cal 10 and psittacosis virus strain 6BC),  Group C streptococcus ,  type 1 pneumococcus ,  Staphylococcus albus ,  Escherichia coli ,  and Serratia marcescens Bizio (ATCC 274).  Solutions of triethylene glycol are known to be antimicrobial toward suspensions of Penicillium notatum spores,  Streptococcus pyogenes (original citation: Beta hemolytic streptococcus Group A ),  Streptococcus pneumoniae (original citation: pneumococcus Type I),  Streptococcus viridans ,  and Mycobacterium bovis (original citation: tubercle bacilli Ravenel bovine-type).  Further, the inactivation of H1N1 influenza A virus on surfaces has been demonstrated.  The latter investigation suggests that triethylene glycol may prove to be a potent weapon against future influenza epidemics and pandemics .