Steroids can worsen existing skin pathologies. Athletes being treated for acne often stop responding to normal treatment regimens if they also continue to use the drugs. Some cases of comparatively benign acne can progress to the disfiguring inflammatory types. Psoriasis is an autoimmune disease in which, for unknown reasons, immune cells attack skin cells, resulting in red, scaly patches. One bodybuilder had controlled his psoriasis condition through the use of a topical cream, but when he began using steroids, his condition considerably deteriorated. Eventually his psoriasis became resistant to treatment. But when he stopped using steroids, the psoriasis stabilized and again responded to simple skin-cream treatment. 6
Usually you won’t have a problem with a high dose for five days if given as a burst to treat a medical problem.
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